The latest research indicates that typical male pattern baldness results from the hyperactivity of the enzyme 5-alpha-reductase. This enzyme elevates the levels of the male hormone dihydrotestosterone (DHT), resulting in the constriction of blood arteries that feed oxygen and nutrients to the hair follicles, ultimately leading to their gradual and ongoing perish. Subsequent to this discovery, other vitamins and nutritional supplements were identified that could block the synthesis of the DHT hormone, hence potentially postponing the male-pattern baldness process.
Vitamins and dietary supplements for male hair loss:
Zinc
Zinc is a mineral present at notably elevated concentrations in brain tissue, kidneys, liver, eyes, and the male reproductive system. The human body contains a zinc reservoir of approximately 3 grams, which is a crucial element in the function of over 200 enzymes. These enzymes are vital for immune system activity, DNA synthesis, wound and burn healing, bone formation, cell replication, and protection against free radicals, among other processes. Zinc is crucial for the optimal performance of insulin, which regulates blood glucose levels, for modulating fat formation in the skin’s sebaceous glands, and for the appropriate operation of the senses of taste and smell.
Research indicates that zinc positively influences hair and scalp health, as well as male-pattern hair loss. Zinc suppresses the function of the enzyme 5-alpha-reductase, hence diminishing the concentration of the male hormone in the scalp and delaying hair loss in areas typical of male pattern baldness.
Suggested dose
The advised daily intake is 15 milligrams of zinc. Individuals in good health that consume a diverse diet comprising beef, poultry, and eggs typically obtain sufficient zinc from their nutrition.
It is advisable to choose zinc picolinate as a dietary supplement due to its superior bioavailability. In this case, a single tablet of 12–15 mg per day is typically adequate. Alternative zinc supplements exhibit diminished bioavailability, needing increased dosages.
It is advisable to consume zinc in the evening prior to sleep, as it promotes relaxation and produces drowsiness.
Gamma-linolenic acid (GLA)
Gamma-linolenic acid is a vital omega-6 fatty acid. Although elevated consumption of most fatty acids in this category fosters inflammation and heightens susceptibility to infections and diseases, gamma-linolenic acid functions as an anti-inflammatory agent and mitigates adverse effects.
GLA functions as an inhibitor of the enzyme required to convert the male hormone testosterone into its more active version, dihydrotestosterone. This pharmacological inhibition is crucial in decelerating testosterone-dependent processes, such as male pattern baldness.
The advised daily dosage is 300 milligrams of GLA supplements. Doses exceeding this may be detrimental to the liver.
saw palmetto (Dwarf Palm)
Saw palmetto, or the dwarf palm, is a smaller palm characterized by expansive, broad leaves that create a crown and produces dark crimson fruits. For millennia, Native Americans have utilized its fruits to address urinary tract infections and male genital issues, along with other symptoms now identifiable as benign prostatic hyperplasia.
Male pattern baldness, which is typified by balding at the crown and a receding hairline at the temples, may also be treated with saw palmetto, according to promising results from current experiments. This form of hair loss is influenced by the hormone dihydrotestosterone and results from the hyperactivity of the enzyme 5-alpha-reductase. This enzyme elevates dihydrotestosterone levels, resulting in the constriction of blood vessels supplying oxygen and nutrients to hair follicles, ultimately leading to their progressive and continual breakdown.
Consistent consumption of saw palmetto restricts the enzyme 5-alpha-reductase activity in scalp hair follicles, thereby diminishing dihydrotestosterone levels in the scalp. This method prevents the breakdown of hair follicles in areas typical of male pattern baldness.
Suggested dose
The advised daily dosage is 500 milligrams of standardized extract, to be administered three times day with meals. It is advisable to pair saw palmetto with a zinc supplement.
To guarantee the efficacy of baldness treatment with vitamins and nutritional supplements, a thorough medical consultation is essential, encompassing meticulous blood testing, identification of the baldness type, and ongoing assessment of treatment outcomes.
The hair loss treatment for men at Dr. Udi Barr’s clinic is tailored to each patient based on their age, rate of hair loss, and individual health status. Reach out to us for further information and to arrange a meeting.
The Complete Israeli Guide to Nutritional Supplements, by Dr. Udi Barr and Yaffe Shir-Raz, Keter Publishing, 2008